evaluation of teaching through lecture with new methods of student-centered teaching in medical students

background: research about teaching methods and students&apos; education is an important subject which can improve the quality of education. this study was performed to compare three educational methods: teaching through lecture, presentation by small group of students, student&apos;s search and study of topics before the class. methods: this quasi-experimental study was conducted on 42 students&apos; of 5th semesters of basic science course, in mashhad faculty of medicine. in order to compare the learning outcomes, usefulness and clarity of subjects, similar three subjects were selected from health education sessions and presented with one of the three methods. descriptive examinations of the most important entries were taken with a similar structure at the end of each session. the collected data was analyzed by using spss 11.5 software and statistical tests of repeated measurements, mcnemar and spearman correlation. results:  mean of exam scores, in method of study before the class was the highest and after that students&apos; presentation was more than the lecture (p <0.001). the frequency of students who had great interest in students&apos; small group presentation, search and study before class was more than lecture method (p =0.02). conclusion: interest rate and student exam scores in student-centered teaching methods were more than the lecture by the teacher. this study showed that students&apos; active role in teaching process can provide a better outcome and higher satisfaction for learners.